We have completed a Phase 2 Clinical Trial of a novel therapy. Scarring affects some 6 million people in the UK and results in physical and psychological morbidity. Physical symptoms include a red, raised, itchy scar that may take longer than desired to mature. Past work has demonstrated that if injected at the time of wounding, insulin has the potential to modulate the healing process. The study involves 90 women undergoing non-cancer bilateral breast surgery being randomised to receive treatment with placebo or insulin intradermally.
This study is the first of its kind to involve both NHS patients at the Queen Victoria Hospital and private patients at the McIndoe Surgical Centre. It has been adopted as a portfolio project as part of the National Institute of Health Research Comprehensive Local Research Network (NIHR CLRN).